The Blood Oxygen GuideFrom your bed to the summit
The guide

What happens to your blood oxygen at altitude?

By GyroscopeUpdated November 14, 202612 sources
On this page
  1. Why would a normal number fool you up high?
  2. Why is there less oxygen up high?
  3. A simple way to picture it
  4. How much oxygen is in each breath?
  5. What does your number do as you climb?
  6. Who gets altitude sickness?
  7. How do you know if you’re getting it?
  8. How fast should you go up?
  9. Who should talk to a doctor before going high?
  10. What if you live up high?

Each breath carries less oxygen the higher you go, about 82% of the sea-level amount in Denver and 69% at 10,000 feet. Your number holds up well to about 8,000 feet, then falls fast. Pace the elevation you sleep at, and let symptoms decide, because the number can’t tell you if you’re getting sick.

911

Call 911 if you have trouble breathing, chest pain or pressure that doesn't go away, new confusion, can't stay awake, or your lips, nail beds or skin look pale, gray or blue, whatever the number says.

What we’d do

Plan the trip by where you sleep. Coming from low ground, keep the first night under 9,000 feet. Above 9,800 feet, sleep no more than 1,650 feet higher each night, and add a rest night for every 3,300 feet. Each morning, check for headache, stomach trouble, tiredness and dizziness. With symptoms, don’t go higher, and go down if they get worse. Leave the oximeter in the bag as a judge of whether you’re well.

If you remember three things

  1. A quarter of Colorado visitors get altitude sickness. The CDC puts it at 25% of visitors sleeping above 8,000 feet there.
  2. The number won’t warn you. People with altitude sickness usually show a normal number for the altitude, the CDC says.
  3. Where you sleep is what you pace. Under 9,000 feet the first night, then 1,650 feet a night above 9,800.

Why would a normal number fool you up high?

People bring an oximeter on a trek for the same reason they’d bring a thermometer, expecting it to say when something’s wrong. Up high that logic breaks. Everyone’s number drops, sick or well, and the CDC says people with altitude sickness usually show a number that’s within the normal range for the altitude, or a little lower.

Doctors who study altitude add that the normal number at a given elevation should be thought of as a range, and that decisions shouldn’t rest on small differences between people or from one check to the next. A fit friend at 88 and a sick friend at 86 can’t be told apart by the numbers.

Why is there less oxygen up high?

The air is the same mix all the way up. Oxygen makes up about 21% of it at every altitude. What changes is the pressure. The higher you go, the less air is pressing down from above, so each breath holds fewer molecules of everything, oxygen included.

A simple way to picture it

Think of a bag of trail mix where one handful in five is peanuts. On the mountain, the mix in the bag is the same, but your scoop gets smaller. You still get one peanut in five, just fewer of them in each scoop.

A packed carry-on bag

How much oxygen is in each breath?

ElevationOxygen in each breath, against sea level (NASA formula)The CDC’s risk if you sleep there
Sea level100%
Denver, 5,280 ft (1,609 m)About 82%Low
8,000 ft (2,438 m)About 74%Low, but anyone not used to it is at risk from here up
10,000 ft (3,048 m)About 69%Medium
Cusco, about 11,150 ft (3,400 m)About 66%Medium, at the edge of high
14,000 ft (4,267 m)About 59%High

The CDC gives the same 69% for 10,000 feet. Its risk bands for the elevation you sleep at are low under 9,000 feet, medium from 9,000 to 11,150, and high above that. Oxygen by elevation works it out for any town or height.

What does your number do as you climb?

Your hemoglobin holds onto oxygen well while there’s plenty around, then lets go fast once the air gets thin. That’s why the number barely moves at first.

In the Apple Watch study of 33,080 people, the night average fell about 1.2 points for every kilometre (3,300 feet) higher people lived, and by day about 0.8. The straight line held to about 8,200 feet and bent above it.

Where you sleepTypical watch night average, age 40, BMI 25Typical watch day, age 40, BMI 25
Sea levelAbout 93.5 to 98.4About 94.4 to 98.9
Denver, 5,280 ftAbout 91.6 to 96.5About 93.1 to 97.5
8,200 ftAbout 90.6 to 95.4About 92.3 to 96.8
Above 8,200 ftNo band. The number becomes a wide range

Above the bands, there’s one real example. In a study published in 2021, 13 healthy lowlanders made a fast climb from about 3,700 feet to 14,957 feet (4,559 m). Their blood tests averaged 75%, a medical finger oximeter showed 81% and a Garmin Fenix 5X Plus 85%. The Garmin was 7 points too high on average, and the researchers said it “cannot be recommended” for oxygen at high altitude.

If your skin is darker, any sensor up high can show higher than your true oxygen, the same way it can at sea level. In hospital patients whose finger oximeter showed 92 to 96, true oxygen was under 88 for 11.7% of Black patients’ measurements and 3.6% of White patients’.

Who gets altitude sickness?

In 1993 a team led by Honigman surveyed 3,158 adult visitors at Colorado resorts from 6,300 to 9,700 feet. A quarter got acute mountain sickness, and about two in three of those got it within the first 12 hours. Visitors who lived below 3,000 feet were 3.5 times as likely to get it, and people who’d had it before 2.8 times as likely.

The surprise was age. Visitors under 60 were about twice as likely to get it as older visitors. More than half of the people who got sick cut back on their activities.

How do you know if you’re getting it?

Symptoms usually start 2 to 12 hours after you arrive. The doctors who study it use a simple morning score, the 2018 Lake Louise score. Rate each of four symptoms from 0 (none) to 3 (severe, hard to function).

  • Headache
  • Stomach, from poor appetite or nausea up to vomiting
  • Tiredness or weakness
  • Dizziness or light-headedness

Three points or more, with at least one from the headache, after a recent climb and at least 6 hours at the new elevation, is acute mountain sickness. Sleep used to be on the list and was dropped in 2018, because poor sleep up high comes from the thin air itself. The CDC adds that symptoms that start after 3 days at the same elevation shouldn’t be put down to altitude sickness.

Two rarer forms of altitude illness are emergencies. One affects the brain (high-altitude cerebral edema) and brings confusion, clumsiness and drowsiness. The other is fluid in the lungs (high-altitude pulmonary edema), which starts with chest congestion, a cough, much more breathlessness than usual on effort and falling performance, and there oxygen numbers of 50% to 70% are common. Any of those signs up high means get medical help now.

How fast should you go up?

The CDC’s travel guide paces a trip by the elevation you sleep at.

  1. From under 4,000 feet, don’t sleep at 9,000 feet or higher the first night.
  2. Above 9,800 feet, sleep no more than 1,650 feet higher than the night before.
  3. Above 9,800 feet, add an extra night with no gain for every 3,300 feet you climb.
  4. Never go higher to sleep with symptoms. Go down if they get worse despite rest. Going down 1,000 feet or more usually helps quickly.

Two common trips break the first rule. Flying from the coast to a ski town at about 9,600 feet puts your first night over the 9,000-foot line, and one night in Denver on the way fixes it. Flying into Cusco, at about 11,150 feet, puts you there on night one, and our trip tool suggests sleeping lower first, near Machu Picchu, then going up. It flags every night that breaks a rule and finds the one change that clears the most.

The CDC also names a prescription medicine, acetazolamide, for medium and high risk trips. Ask your doctor whether it fits yours.

Who should talk to a doctor before going high?

The CDC says people with heart disease, chronic lung disease or sleep apnea should talk to a doctor who knows altitude medicine before they go. It advises people with severe sleep apnea to avoid high-altitude travel unless they have supplemental oxygen.

What if you live up high?

Then your usual number is lower, and that’s your normal. MedlinePlus notes numbers can be lower at higher elevations. People living around Denver often sit a point or two under sea-level numbers. A new awake number at or under 92 is still a reason to call your doctor.

The sceptic says

I’ll bring an oximeter and turn back if it drops too far. A hard number beats guessing how I feel.

I’m young, so I’ll be fine. Altitude sickness is for older people.

The reply

The number can’t make that call. People with altitude sickness usually show a normal number for the altitude, and a Garmin showed 7 points high at 15,000 feet. The morning symptom check is the test the doctors use.

Being young didn’t help. In 3,158 Colorado visitors, people under 60 were about twice as likely to get it. Where people lived and whether they’d had it before were the strongest factors in that study.

12 sources
  1. CDC Yellow Book, High-Altitude Travel and Altitude Illnesscdc.gov
  2. NASA Glenn Research Center, Earth Atmosphere Model, metric unitsgrc.nasa.gov
  3. Case Western Reserve University, Altitude project, Oxygen Deliverycaslabs.case.edu
  4. Shapiro I and others, Pulse oximetry values from 33,080 participants in the Apple Heart and Movement Study, npj Digital Medicine, 2023pmc.ncbi.nlm.nih.gov
  5. Luks AM and Swenson ER, Pulse oximetry at high altitude, High Altitude Medicine and Biology, 2011europepmc.org
  6. Schiefer LM and others, Validity of peripheral oxygen saturation measurements with the Garmin Fenix 5X Plus wearable device at 4559 m, Sensors, 2021europepmc.org
  7. Honigman B and others, Acute mountain sickness in a general tourist population at moderate altitudes, Annals of Internal Medicine, 1993europepmc.org
  8. Roach RC and others, The 2018 Lake Louise Acute Mountain Sickness Score, High Altitude Medicine and Biology, 2018pmc.ncbi.nlm.nih.gov
  9. Collins JA and others, Relating oxygen partial pressure, saturation and content: the haemoglobin-oxygen dissociation curve, Breathe, 2015pmc.ncbi.nlm.nih.gov
  10. MedlinePlus, Pulse Oximetry, US National Library of Medicine, updated September 12, 2024medlineplus.gov
  11. Sjoding MW and others, Racial bias in pulse oximetry measurement, New England Journal of Medicine, 2020pmc.ncbi.nlm.nih.gov
  12. CDC, Symptoms of COVID-19, emergency warning signscdc.gov
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